Long-term potentiation expands information content of hippocampal dentate gyrus synapses

An approach combining signal detection theory and precise 3D reconstructions from serial section electron microscopy (3DEM) was used to investigate synaptic plasticity and information storage capacity at medial perforant path synapses in adult hippocampal dentate gyrus in vivo.

Balanced excitation and inhibition are required for high-capacity, noise-robust neuronal selectivity

Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of noise, we determine the robustness of single-neuron stimulus selective responses and the robustness of attractor states of networks of neurons performing memory tasks.

Thirst-associated preoptic neurons encode an aversive motivational drive

Water deprivation produces a drive to seek and consume water. How neural activity creates this motivation remains poorly understood.

Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators

Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling the function of neuronal circuits but is challenging due to the limited performance of existing tools.

Distortion of passive scalar structure during suction-based plume sampling

Elsevier Sensors and Actuators B: Chemical
Studies of plume dynamics and olfaction often rely on photoionization detectors (PID) to quantify spatiotemporal distributions of passive scalars (gases, vapors, odors). However, the potential for PID suction to distort filaments and to modify the resulting sensed time record remains unclear.