Of flies, mice and neural control of food intake: lessons to learn from both models
Current Opinion in Neurobiology
In this review, we discuss the recent literature on neural control of food intake behaviors in mice and flies with the view that these two model organisms complement one another in efforts to uncover conserved principles brains use to regulate energy metabolism and food ingestion.
On the relationship between predictive coding and backpropagation
This manuscript reviews and extends recent work on the mathematical relationship between predictive coding and backpropagation for training feedforward artificial neural networks on supervised learning tasks.
Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes
Intravital confocal microscopy and two-photon microscopy are powerful tools to explore the dynamic behavior of immune cells in mouse lymph nodes (LNs), with penetration depth of ~100 and ~300 μm, respectively.
Multiphoton imaging of neural structure and activity in Drosophila through the intact cuticle
We developed a multiphoton imaging method to capture neural structure and activity in behaving flies through the intact cuticle. Our measurements showed that the fly head cuticle has surprisingly high transmission at wavelengths >900nm.
Bioluminescent optogenetic (BL-OG) activation of neurons during mouse postnatal brain development
Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG thus confers both optogenetic and chemogenetic access within the same genetically targeted neuron.
Evaluation of force feedback in walking using joint torques as “naturalistic” stimuli
Journal of Neurophysiology
Control of adaptive walking requires the integration of sensory signals of muscle force and load. We have studied how mechanoreceptors (tibial campaniform sensilla) encode “naturalistic” stimuli derived from joint torques of stick insects walking on a horizontal substrate.
A three-dimensional musculoskeletal model of the dog
We describe here the methods we used to create a detailed musculoskeletal model with 84 degrees of freedom and 134 muscles. Our model has three key-features: three-dimensionality, scalability, and modularity.
3D printing hydrogel-based soft and biohybrid actuators: A mini-review on fabrication techniques, applications, and challenges
Frontiers in Robotics and AI
This mini-review surveys existing research efforts to inspire the development of novel fabrication techniques using hydrogel building blocks and identify potential future directions. In this article, existing 3D fabrication techniques for hydrogel actuators are first examined.
Improving laser standards for three-photon microscopy
Three-photon excitation microscopy has double-to-triple the penetration depth in biological tissue over two-photon imaging and thus has the potential to revolutionize the visualization of biological processes in vivo. However, three-photon microscopy presents new technological challenges.