Christopher Moore
ORCID 0000-0003-4534-1602
POSITIONS HELD
Founding Board Member
Open-Ephys, A Not-for-Profit Corporation
Associate Director
Robert J. and Nancy D. Carney Institute for Brain Science
Professor
Brown University Department of Neuroscience
Co-Founder
DiscoveryEngine, a Not-for-Profit Corporation
AWARDS
2005
School of Science Prize for Excellence in Undergraduate Teaching, MIT
1995
Angus N. MacDonald Excellence in Teaching Award, MIT
EDUCATION
1/1/2002
Visiting Scientist
University of California San Francisco Keck Center
1/1/2002
Postdoctoral Fellow
Martinos Center/Harvard Medical School
1/1/1998
Ph. D
Massachusetts Institute of Technology (MIT)
1/1/1990
B. A.
Oberlin College
Publications
William E. Medendorp, Andreas Bjorefeldt, Emmanuel L. Crespo, Mansi Prakash, Akash Pal, Madison L. Waddell, Christopher I. Moore, Ute Hochgeschwender
Selective postnatal excitation of neocortical pyramidal neurons results in distinctive behavioral and circuit deficits in adulthood
iScience 24
(2021)
Dmitrijs Celinskis, Nina Friedman, Mikhail Koksharov, Jeremy Murphy, Manuel Gomez-Ramirez, David Borton, Nathan Shaner, Ute Hochgeschwender, Diane Lipscombe, Christopher Moore
Miniaturized Devices for Bioluminescence Imaging in Freely Behaving Animals
(2020)
Manuel Gomez‐Ramirez, Alexander I. More, Nina G. Friedman, Ute Hochgeschwender, Christopher I. Moore
The BioLuminescent‐OptoGenetic in vivo response to coelenterazine is proportional, sensitive, and specific in neocortex
Journal of Neuroscience Research 98
(2019)
Hyeyoung Shin, Robert Law, Shawn Tsutsui, Christopher I Moore, Stephanie R Jones
The rate of transient beta frequency events predicts behavior across tasks and species
eLife 6
(2017)
Maxwell A. Sherman, Shane Lee, Robert Law, Saskia Haegens, Catherine A. Thorn, Matti S. Hämäläinen, Christopher I. Moore, Stephanie R. Jones
Neural mechanisms of transient neocortical beta rhythms: Converging evidence from humans, computational modeling, monkeys, and mice
Proceedings of the National Academy of Sciences 113
(2016)
Ken Berglund, Jack K. Tung, Bryan Higashikubo, Robert E. Gross, Christopher I. Moore, Ute Hochgeschwender
Combined Optogenetic and Chemogenetic Control of Neurons
Methods in Molecular Biology
(2016)
David Badre, Michael J. Frank, Christopher I. Moore
Interactionist Neuroscience
Neuron 88
(2015)
Dominique L Pritchett, Joshua H Siegle, Christopher A Deister, Christopher I Moore
For things needing your attention: the role of neocortical gamma in sensory perception
Current Opinion in Neurobiology 31
(2015)
Matthew D. Sacchet, Roan A. LaPlante, Qian Wan, Dominique L. Pritchett, Adrian K.C. Lee, Matti Hämäläinen, Christopher I. Moore, Catherine E. Kerr, Stephanie R. Jones
Attention Drives Synchronization of Alpha and Beta Rhythms between Right Inferior Frontal and Primary Sensory Neocortex
The Journal of Neuroscience 35
(2015)
Joshua H Siegle, Dominique L Pritchett, Christopher I Moore
Gamma-range synchronization of fast-spiking interneurons can enhance detection of tactile stimuli
Nature Neuroscience 17
(2014)
Elizabeth A. Normand, Shane R. Crandall, Catherine A. Thorn, Emily M. Murphy, Bettina Voelcker, Catherine Browning, Jason T. Machan, Christopher I. Moore, Barry W. Connors, Mark Zervas
Temporal and Mosaic Tsc1 Deletion in the Developing Thalamus Disrupts Thalamocortical Circuitry, Neural Function, and Behavior
Neuron 78
(2013)
Jakob Voigts, Joshua H. Siegle, Dominique L. Pritchett, Christopher I. Moore
The flexDrive: an ultra-light implant for optical control and highly parallel chronic recording of neuronal ensembles in freely moving mice
Frontiers in Systems Neuroscience 7
(2013)
Christopher I. Moore, Emilie Crosier, Douglas N. Greve, Robert Savoy, Michael M. Merzenich, Anders M. Dale
Neocortical Correlates of Vibrotactile Detection in Humans
Journal of Cognitive Neuroscience 25
(2013)
Catherine E. Kerr, Matthew D. Sacchet, Sara W. Lazar, Christopher I. Moore, Stephanie R. Jones
Mindfulness starts with the body: somatosensory attention and top-down modulation of cortical alpha rhythms in mindfulness meditation
Frontiers in Human Neuroscience 7
(2013)
Joshua H. Siegle, Christopher I. Moore
Cortical Circuits: Finding Balance in the Brain
Current Biology 21
(2011)
Itamar Kahn, Mitul Desai, Ulf Knoblich, Jacob Bernstein, Michael Henninger, Ann M. Graybiel, Edward S. Boyden, Randy L. Buckner, Christopher I. Moore
Characterization of the Functional MRI Response Temporal Linearity via Optical Control of Neocortical Pyramidal Neurons
The Journal of Neuroscience 31
(2011)
Judith D. Schaechter, Casper A. M. M. van Oers, Benjamin N. Groisser, Sara S. Salles, Mark G. Vangel, Christopher I. Moore, Rick M. Dijkhuizen
Increase in Sensorimotor Cortex Response to Somatosensory Stimulation Over Subacute Poststroke Period Correlates With Motor Recovery in Hemiparetic Patients
Neurorehabilitation and Neural Repair 26
(2011)
J. H. Siegle, M. Carlen, K. Meletis, C. I. Moore, J. Ritt
Chronically implanted hyperdrive for cortical recording and optogenetic control in behaving mice
2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
(2011)
Michael M Halassa, Joshua H Siegle, Jason T Ritt, Jonathan T Ting, Guoping Feng, Christopher I Moore
Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles
Nature Neuroscience 14
(2011)
Stephanie R. Jones, Catherine E. Kerr, Qian Wan, Dominique L. Pritchett, Matti Hämäläinen, Christopher I. Moore
Cued Spatial Attention Drives Functionally Relevant Modulation of the Mu Rhythm in Primary Somatosensory Cortex
The Journal of Neuroscience 30
(2010)
David A. Ziegler, Dominique L. Pritchett, Paymon Hosseini-Varnamkhasti, Suzanne Corkin, Matti Hämäläinen, Christopher I. Moore, Stephanie R. Jones
Transformations in oscillatory activity and evoked responses in primary somatosensory cortex in middle age: A combined computational neural modeling and MEG study
NeuroImage 52
(2010)
Christopher I. Moore, Marie Carlen, Ulf Knoblich, Jessica A. Cardin
Neocortical Interneurons: From Diversity, Strength
Cell 142
(2010)
Sujith Vijayan, Greg J. Hale, Christopher I. Moore, Emery N. Brown, Matthew Wilson
Activity in the Barrel Cortex During Active Behavior and Sleep
Journal of Neurophysiology 103
(2010)
Jessica A Cardin, Marie Carlén, Konstantinos Meletis, Ulf Knoblich, Feng Zhang, Karl Deisseroth, Li-Huei Tsai, Christopher I Moore
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2
Nature Protocols 5
(2010)
Dorea Vierling-Claassen, Jessica A. Cardin, Christopher I. Moore, Stephanie R. Jones
Computational Modeling of Distinct Neocortical Oscillations Driven by Cell-Type Selective Optogenetic Drive: Separable Resonant Circuits Controlled by Low-Threshold Spiking and Fast-Spiking Interneurons
Frontiers in Human Neuroscience 4
(2010)
Ulf Knoblich, Joshua H. Siegle, Dominique L. Pritchett, Christopher I. Moore
What do We Gain from Gamma? Local Dynamic Gain Modulation Drives Enhanced Efficacy and Efficiency of Signal Transmission
Frontiers in Human Neuroscience 04
(2010)
Stephanie R. Jones, Dominique L. Pritchett, Michael A. Sikora, Steven M. Stufflebeam, Matti Hämäläinen, Christopher I. Moore
Quantitative Analysis and Biophysically Realistic Neural Modeling of the MEG Mu Rhythm: Rhythmogenesis and Modulation of Sensory-Evoked Responses
Journal of Neurophysiology 102
(2009)
Talia Konkle, Christopher I. Moore
What can crossmodal aftereffects reveal about neural representation and dynamics?
Communicative & Integrative Biology 2
(2009)
Matthew K. Belmonte, Yoram S. Bonneh, Yael Adini, Portia E. Iversen, Natacha A. Akshoomoff, Tal Kenet, Christopher I. Moore, Helen J. Simon, John F. Houde, Michael M. Merzenich
Autism Overflows with Syntheses
Neuropsychology Review 19
(2009)
Talia Konkle, Qi Wang, Vincent Hayward, Christopher I. Moore
Motion Aftereffects Transfer between Touch and Vision
Current Biology 19
(2009)
Jessica A. Cardin, Marie Carlén, Konstantinos Meletis, Ulf Knoblich, Feng Zhang, Karl Deisseroth, Li-Huei Tsai, Christopher I. Moore
Driving fast-spiking cells induces gamma rhythm and controls sensory responses
Nature 459
(2009)
Rosa Cao, Bryan T. Higashikubo, Jessica Cardin, Ulf Knoblich, Raddy Ramos, Mark T. Nelson, Christopher I. Moore, Joshua C. Brumberg
Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro
Cleveland Clinic Journal of Medicine 76
(2009)
Yoram S. Bonneh, Matthew K. Belmonte, Francesca Pei, Portia E. Iversen, Tal Kenet, Natacha Akshoomoff, Yael Adini, Helen J. Simon, Christopher I. Moore, John F. Houde, Michael M. Merzenich
Cross-modal extinction in a boy with severely autistic behaviour and high verbal intelligence
Cognitive Neuropsychology 25
(2008)
Christopher I. Moore, Rosa Cao
The Hemo-Neural Hypothesis: On The Role of Blood Flow in Information Processing
Journal of Neurophysiology 99
(2008)
Jason T. Ritt, Mark L. Andermann, Christopher I. Moore
Embodied Information Processing: Vibrissa Mechanics and Texture Features Shape Micromotions in Actively Sensing Rats
Neuron 57
(2008)
Stephanie R. Jones, Dominique L. Pritchett, Steven M. Stufflebeam, Matti Hämäläinen, Christopher I. Moore
Neural Correlates of Tactile Detection: A Combined Magnetoencephalography and Biophysically Based Computational Modeling Study
The Journal of Neuroscience 27
(2007)
Catherine E. Kerr, Rachel H. Wasserman, Christopher I. Moore
Cortical Dynamics As A Therapeutic Mechanism for Touch Healing
The Journal of Alternative and Complementary Medicine 13
(2007)
J. D. Schaechter
Structural and functional plasticity in the somatosensory cortex of chronic stroke patients
Brain 129
(2006)
Mark L Andermann, Christopher I Moore
A somatotopic map of vibrissa motion direction within a barrel column
Nature Neuroscience 9
(2006)
Sara W. Lazar, Catherine E. Kerr, Rachel H. Wasserman, Jeremy R. Gray, Douglas N. Greve, Michael T. Treadway, Metta McGarvey, Brian T. Quinn, Jeffery A. Dusek, Herbert Benson, Scott L. Rauch, Christopher I. Moore, Bruce Fischl
Meditation experience is associated with increased cortical thickness
NeuroReport 16
(2005)
Christopher I. Moore
Frequency-Dependent Processing in the Vibrissa Sensory System
Journal of Neurophysiology 91
(2004)
Mark L Andermann, Jason Ritt, Maria A Neimark, Christopher I Moore
Neural Correlates of Vibrissa Resonance
Neuron 42
(2004)
Catherine E. Garabedian, Stephanie R. Jones, Michael M. Merzenich, Anders Dale, Christopher I. Moore
Band-Pass Response Properties of Rat SI Neurons
Journal of Neurophysiology 90
(2003)
Maria A. Neimark, Mark L. Andermann, John J. Hopfield, Christopher I. Moore
Vibrissa Resonance as a Transduction Mechanism for Tactile Encoding
The Journal of Neuroscience 23
(2003)
Christopher I. Moore, Chantal E. Stern, Carolyn Dunbar, Sandra K. Kostyk, Anil Gehi, Suzanne Corkin
Referred phantom sensations and cortical reorganization after spinal cord injury in humans
Proceedings of the National Academy of Sciences 97
(2000)
My laboratory studies neocortical dynamics, changes in activity that occur on millisecond to second time scales. We seek to understand the meaning of these dynamics for perception, and the mechanisms that generate them. We are currently testing hypotheses as to the computational value and origins of neocortical oscillations, and the role that non-neuronal systems (e.g., the vasculature) may play in information processing. To address these questions, we integrate behavior, optogenetics, electrophysiology and imaging.